Current Projects - American Chemistry Council

Abstracts for Current Projects

Project abstracts are a primary source of information regarding the status and progress for LRI’s currently funded projects. These abstracts are provided each year by the principal investigators as a key part of their research agreement with LRI. Links to abstracts for each of these projects are located at the end of the project titles in the list below. See the ACC Research Catalog to access publications from current and past LRI research projects.

Current LRI Research Project Portfolio: 14

Advance Understanding of Consumer Exposures: Predictive Models for Generating Exposure Estimates

Project Title: Expanding and Improving the EAS-E Suite Platform for Exposure Modeling
Principal Investigator: Jon Arnot, Ph.D.
Research Institution: ARC Arnot Research & Consulting Inc.

Project Title: Creating and Sustaining Successful Public-Private Partnerships (PPPs) for Environmental Monitoring Programs: Principles and Elements
Principal Investigator: Judy LaKind, Ph.D.
Research Institution: LaKind Associates, LLC

Project Title: Exposure Research Using Robotics to Measure Concentrations / Verify Exposure Model Predictions
Principal Investigator: Albania Grosso
Research Institution: Lower Olefins and Aromatics REACH Consortium (A.G.) and Stantec (H.L.)

Integrate Hazard and Exposure to Assess Risks from Chemicals: New Tools for Linking the Data

Project Title: Exploring Artificial Intelligence Technologies to Develop a “Causal Research Assistant”
Principal Investigator: Tony Cox, Ph.D.
Research Institution: Cox Associates

Project Title: Population Life-course Exposure to Health Effects Model (PLETHEM) - Continued Platform Development and Education and Outreach
Principal Investigator: Marjory Moreau, Ph.D.
Research Institution: ScitoVation

Project Title: Development of a Tiered Approach for the Application of In Vitro to In Vivo Extrapolation (IVIVE) for Developmental Toxicity in Support of New Approach Method (NAM)- Based Chemical Safety Assessments
Principal Investigator: Harvey Clewell, Ph.D.
Research Institution: Ramboll

Improve Chemical Safety Testing Technologies: Design Fit-for-Purpose Assays and Advance Data Interpretation

Project Title: Omics for Assessing Signatures for Integrated Safety (OASIS) Consortium
Consortium Manager: Chrissy Crute, Ph.D.
Research Institution: Health and Environmental Sciences Institute (HESI)

Project Title: Exploring Tissue Chips for Toxicity Testing: Testing Consortium at Texas A&M University (TEX-VAL)
Principal Investigators: Ivan Rusyn, Ph.D.,; Courtney Sakolish, Ph.D.,; Clifford Stephan Ph.D.
Research Institution: Texas A&M University

Project Title: Development of a Fit-For-Purpose In Vitro Model of Lung Toxicity
Principal Investigator: Les Recio, Ph.D.
Research Institution: ScitoVation

Project Title: Application of Toxicogenomics in Next-Generation Risk Assessment
Principal Investigator: Rasim Barutcu, Ph.D.
Research Institution: ScitoVation

Project Title: Advancing Respiratory Tract Cell Culture NAM Models for Risk-Based Decision-Making
Principal Investigator: Joanne Wallace, Ph.D.; Seyoum Ayehunie, Ph.D.
Research Institution: Charles River Laboratories Edinburgh and MatTek

Address Topical Challenges Faced by the Chemical Industry: Novel Techniques and Tools

Project Title: Evaluating Morphological, Behavioral & Transcriptomic Responses in the Zebrafish Developmental Toxicity Assay to Chemical Mixtures Commonly Associated with Environmental and Human Biomonitoring Studies
Principle Investigator: Robyn Tanguay, Ph.D.
Research Institution: Oregon State University

Project Title: Developmental Toxicity NAMs Scoping Review Update
Principal Investigators: ACC LRI Strategic Science Team
Research Institution: ACC LRI

Project Title: Developing In Vitro Metabolic Clearance Data to Support Development of the Internal Threshold of Toxicological Concern (iTTC)
Principal Investigator: Sherry Black
Research Institution: RTI

Project Title: A Comprehensive Review and Appraisal of Frameworks, Methods, Metrics, and Data Used in Assessments of Communities with Environmental Justice Concerns
Principal Investigator: William Rish, Ph.D; Ann Verwiel
Research Institution: ToxStrategies