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Diisocyanates Hydrolysis

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Erin Dickison
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When Water Meets Diisocyanates: A Hydrolysis Story

Because diisocyanates are highly reactive chemicals, you might wonder how they behave in the environment. Diisocyanates react rapidly with water in a process called hydrolysis. Learn more about what happens during the diisocyanate hydrolysis reaction for these incredible chemical building blocks for many of the products we use every day.


Supporting Information:

Fate of Methylenediphenly Diisocyanate and Toluene Diisocyanate in the Aquatic Environment

Yoshikuni Yakabe, Karen M. Henderson, William C. Thompson, Denis Pemberton, Bernard Tury, and Robert E. Bailey (1999), Environmental Science & Technology, 33 (15), 2579-2583. Available at https://doi.org/10.1021/es981350c

Homogenous Hydrolysis of 4,4’-methylenediphenyl diisocyanate (MDI) in Water

Michael Neuland, Hans Allmendinger, Hans-Georg Pirkl, Robert J. West & Patrick M. Plehiers (2021), Toxicological & Environmental Chemistry. Available at https://doi.org/10.1080/02772248.2021.2009480