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The Evolving Epidemiology of Nasopharyngeal Carcinoma. Cancer Epidemiol Biomarkers.

Authors: Ellen T. Chang, Weimin Ye, Yi-Xin Zeng and Hans-Olov Adami.

Findings from this case–control study provide new insight into the epidemiology of NPC. Recent findings from other studies include a protective association with infectious mononucleosis, suggesting a causal role of early EBV infection; familial risk conferred by shared genetic variation in the host antibody-mediated immune response to EBV infection; and an unclear association with occupational exposure to formaldehyde.