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Polyol Resin Blends Safety and Handling Guidelines 

The Center for the Polyurethanes Industry (CPI) has prepared this guide to provide important health and safety considerations associated with working with polyol resin blends. 

Polyurethane foams are often made using “systems,” sometimes called “A-side” and “B-side,” or “iso side” and “resin side.” It is important to know which side of the system (“A-side” or “B-side”) is the diisocyanate and which is the polyol resin blend. The hazards of the polyol resin are different from those of the diisocyanates, and different precautions should be taken when handling the individual components. This guide gives a brief summary of hazards that may be associated with the “resin side” of systems and addresses important issues to consider in the safe handling of these chemicals.

This guide does not provide information about handling the “iso side.” Handling information is contained in other documents produced by CPI. (See “Additional Information” page 4). Similarly, this guide does not contain information on either the hazards associated with solvents used for equipment cleanup or the hazards associated with specific polyol formulations. For that information, refer to the product-specific Safety Data Sheet (SDS), or consult the supplier.

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American Chemistry Council

The American Chemistry Council’s mission is to advocate for the people, policy, and products of chemistry that make the United States the global leader in innovation and manufacturing. To achieve this, we: Champion science-based policy solutions across all levels of government; Drive continuous performance improvement to protect employees and communities through Responsible Care®; Foster the development of sustainability practices throughout ACC member companies; and Communicate authentically with communities about challenges and solutions for a safer, healthier and more sustainable way of life. Our vision is a world made better by chemistry, where people live happier, healthier, and more prosperous lives, safely and sustainably—for generations to come.