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Measurement of endogenous versus exogenous formaldehyde-induced DNA-protein crosslinks in animal tissues by stable isotope labeling and ultrasensitive mass spectrometry.

Authors: Lai, Yongquan, Rui Yu, Hadley J. Hartwell, Benjamin C. Moeller, Wanda M. Bodnar, and James A. Swenberg.

The formation, accumulation, and hydrolysis of DNA-protein crosslinks of both exogenous and endogenous formaldehyde. The results show that inhaled formaldehyde only reached rat and monkey noses, but not tissues distant to the site of initial contact.

Cancer Relationship Plausibility Formaldehyde
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Foundation for Chemistry Research & Initiatives

The Foundation for Chemistry Research and Initiatives (Foundation), is a 501(c)(3) tax-exempt organization established by the American Chemistry Council (ACC). Through partnerships with academia, research institutions, governmental and non-governmental organizations, and private corporations, the Foundation supports scientific research on various chemistries; the development of training programs for the safe use and application of products; and programs demonstrating chemistry’s contribution and benefits to society.

The Foundation was established in 1995 as the Research Foundation for Health and Environmental Effects (RFHEE).