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Formation, accumulation, and hydrolysis of endogenous and exogenous formaldehyde-induced DNA damage.

Authors: Yu, Rui, Yongquan Lai, Hadley J. Hartwell, Benjamin C. Moeller, Melanie Doyle-Eisele, Dean Kracko, Wanda M. Bodnar, Thomas B. Starr, and James A. Swenberg.

Evaluated the plausibility for inhaled formaldehyde to reach distal sites in rat and monkey models. The study indicated that inhaled formaldehyde was found to reach nasal respiratory epithelium, but not other tissues distant to the site of initial contact.

Foundation for Chemistry Research & Initiatives

The Foundation for Chemistry Research and Initiatives (Foundation), is a 501(c)(3) tax-exempt organization established by the American Chemistry Council (ACC). Through partnerships with academia, research institutions, governmental and non-governmental organizations, and private corporations, the Foundation supports scientific research on various chemistries; the development of training programs for the safe use and application of products; and programs demonstrating chemistry’s contribution and benefits to society.

The Foundation was established in 1995 as the Research Foundation for Health and Environmental Effects (RFHEE).